50 is taking aim at Oprah accusing her of discriminating against rappers. He says Oprah rarely invites rappers to her show as this will upset her white audience.

50 cent slams Oprah

"I think she caters to older white women. Oprah’s audience is my audience’s parents. So I couldn’t care less about Oprah or her show."

I do think 50 is somewhat right, remember when Ludacris was on Oprah? He was invited to promote his film “Crash” and was lectured about his lyrics.